3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

74licensed products
1 monograph
Powder, Capsule, Liquid +2

Health Canada Monographs

1

Approved Health Claims

7
  • Helps (temporarily) to support/promote alertness and wakefulness, and to enhance cognitive performance
  • Helps (temporarily) to support/promote mental sharpness/alertness
  • Helps (temporarily) to relieve/reduce fatigue, to promote endurance, and to enhance motor performance
  • Helps (temporarily) to enhance (physical) energy
  • Helps (temporarily) to relieve/reduce fatigue/tiredness
  • The above uses can be combined on the product label (e.g. Helps temporarily to support mental alertness and reduce fatigue)
  • The terms ‘Helps’ or ‘Helps to’ can be used interchangeably on the label

Approved Dose Ranges

1
PopulationDose RangeFrequency
Adults 18 years and older100–200 milligramsper day

Cautions & Contraindications

10
cautionAsk a health care practitioner/health care provider/health care professional/doctor/physician before use if you have high blood pressure or glaucoma (Cornelis and El-Sohemy 2007, Chandrasekaran et al. 2005, Noordzij et al. 2005, Avisar et al. 2002, Arya et al. 2000, Jee et al. 1999, Creighton and Stanton 1990).
caution1 Note: This statement is also required at subtherapeutic quantities for products providing 40 mg or more caffeine per day from all sources for Class II and III applications.
cautionAsk a health care practitioner/health care provider/health care professional/doctor/physician before use if you are pregnant, breastfeeding, or attempting to conceive (Nawrot et al. 2003).
cautionWhen using this product avoid taking other health products, foods or beverages that contain caffeine and/or increase blood pressure (FDA 2023; Bui et al. 2006; Bouchard et al. 2005; Haller et al. 2005; NIH 2004; Berardi et al. 2002; Vahedi et al. 2000; Zimmerman 1992).
contraindicationDo not use if you have high blood pressure or glaucoma (Cornelis and El-Sohemy 2007, Chandrasekaran et al. 2005, Noordzij et al. 2005, Avisar et al. 2002, Arya et al. 2000, Jee et al. 1999, Creighton and Stanton 1990).
adverse_reactionStop use and ask a health care practitioner/health care provider/health care professional/doctor/physician if hypersensitivity/allergy occurs (Infante et al. 2003; Hinrichs et al. 2002).
adverse_reactionStop use and ask a health care practitioner/health care provider/health care professional/doctor/physician if symptoms such as chest pain and irregular heartbeat occur (Higgins and Babu 2013).
adverse_reactionStop use and ask a health care practitioner/health care provider/health care professional/doctor/physician if nervousness, anxiety, insomnia, tremor and/or headache occur (IOM 2001, Zhang 2001, Sawynok 1995).
adverse_reactionWhen using this product diuretic effect may occur.
adverse_reaction1 Note: This statement is also required at subtherapeutic quantities for products providing 40 mg or more caffeine per day from all sources for Class II and III applications.

Alternative Names

11
Caffeine(common)Camellia sinensis(common)Coffea arabica(common)Coffea canephora(common)Cola acuminata(common)Ilex guayusa(common)Ilex paraguariensis(common)Paullinia cupana(common)Theobroma cacao(common)1,3,7-Trimethylxanthine3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Common Quantities in Licensed Products

10
200 mg15 licensed products
50 mg9 licensed products
150 mg9 licensed products
100 mg6 licensed products
200 milligrams6 licensed products
100 milligrams5 licensed products
5 mg4 licensed products
75 mg4 licensed products
90 mg4 licensed products
125 mg4 licensed products

Check your 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione product's compliance

Validate your formulation against Health Canada monographs and 74 licensed products containing 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione.

Scan Your Product Free