5-Hydroxy-L-tryptophan

181licensed products
1 monograph
Capsule, Tablet, Capsule, hard +2

Health Canada Monographs

1

Approved Health Claims

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  • Helps (to) promote healthy mood balance
  • Helps (to) relieve sleep disturbances associated with mood imbalance
  • Helps (to) relieve symptoms of fibromyalgia
  • Helps (to) reduce the severity and duration of migraine headaches when taken as a preventative (prophylactic)
  • To be used with a program of reduced intake of dietary calories and increased physical activity (if possible) to help in weight management by reducing carbohydrate cravings
  • If a weight management claim is made: Weight management is a long-term process and must therefore, be associated with a long-term intervention. Medicinal ingredient with diuretic properties may be included in weight management products, however no diuretic claim can be applied as it is associated with a short-term duration of use (occasional use only). Stimulant laxatives cannot be present at therapeutic dose in weight management products as their short term duration of use is not compatible with the duration of use for weight management
  • Weight management is a long-term process and must therefore, be associated with a long-term intervention
  • Medicinal ingredient with diuretic properties may be included in weight management products, however no diuretic claim can be applied as it is associated with a short-term duration of use (occasional use only)
  • Stimulant laxatives cannot be present at therapeutic dose in weight management products as their short term duration of use is not compatible with the duration of use for weight management

Approved Dose Ranges

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PopulationDose RangeFrequency
Adults 18 years and older150–300 milligramsper day
Adults 18 years and older300–400 milligramsper day
Adults 18 years and older200–600 milligramsper day
Adults 18 years and older750–900 milligramsper day
Adults 18 years and older100–200 milligramsper day

Cautions & Contraindications

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cautionAsk a health care practitioner/health care provider/health care professional/doctor/physician before use if you are taking carbidopa or health products with serotonergic activity such as mood balance supplements, cough medication containing dextromethorphan, pain killers or medications for nausea or migraine (Mayo Clinic Staff 2022; Patel and Marzella 2017; Turner et al 2006).
cautionWhen using this product exercise caution while driving or using machinery, as you may experience drowsiness (Berardi et al. 2002).
cautionAsk a health care practitioner/health care provider/health care professional/doctor/physician if symptoms persist or worsen.
cautionAsk a health care practitioner/health care provider/health care professional/doctor/ physician before use if you are pregnant or breastfeeding.
cautionAsk a health care practitioner/health care provider/health care professional/doctor/ physician before use if you are breastfeeding.
cautionAsk a health care practitioner/health care provider/health care professional/doctor/physician before use if you have a psychological disorder such as anxiety or depression.
contraindicationDo not use if you have scleroderma (Lampert et al. 1992; Sternberg et al. 1980).
contraindicationDo not use if you are taking antidepressants (Mayo Clinic Staff 2022; Patel and Marzella 2017).
contraindicationDo not use if you are pregnant (HC 2010).
adverse_reactionWhen using this product you may experience gastrointestinal discomfort/disturbances (Turner et al. 2006; Byerley et al. 1987).
adverse_reactionStop use and ask a health care practitioner/health care provider/health care professional/doctor/physician if you experience skin hardening, pain or stiffness of muscles or joints, tremors, agitation/confusion, or an increased heart rate (Boyer 2023; Varga 2023; Mayo Clinic Staff 2022; Patel and Marzella 2017; Das et al. 2004; Erner et al. 2003; Lampert et al. 1992; Sternberg et al. 1980).

Alternative Names

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Escherichia coli(common)L-5-HTP(common)L-5-Hydroxytryptophan(common)Saccharomyces cerevisiae(common)5-Hydroxy-L-tryptophanL-5-HTP 1L-5-Hydroxytryptophan

Common Quantities in Licensed Products

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100 mg63 licensed products
50 mg48 licensed products
25 mg29 licensed products
100 milligrams25 licensed products
15 mg23 licensed products
50 milligrams17 licensed products
200 mg15 licensed products
75 mg13 licensed products
33.3 mg8 licensed products
20 mg7 licensed products

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